Commanders @ Falcons Rooting interest: Neither team should be the front-runner to win their respective division, so this game likely impacts the wildcard race. At 0-2 in division play, the Cardinals need to start finding the teams who will struggle the most to win conference games and stay in the playoff hunt.

The SportsLine projection model has revealed its Arizona vs. Seattle picks for the 2025 NFL Week 4 'Thursday Night Football' game

What was the Seattle Seahawks vs Arizona Cardinals score? Look back at Thursday Night Football score updates from NFL Week 4 game on Sept. 25, 2025.

Through the first four games of 2025 one thing is clear; the Arizona Cardinals have a problem on the offense that, if not fixed, could sink the season.

Seattle avoided a major collapse once Jason Myers drilled a 52-yard field goal with no time left in regulation to escape the desert with a 23-20 victory, moving to 3-1 on the season and staying in position to compete for the division title. Despite the late rally, the Cardinals fall to 2-2 after winning their first two games to start the year.

Arizona Cardinals tight end Trey McBride received an NFL fine for a play that took place in Week 3's loss to the 49ers.

The unfortunate moment that led to Arizona's 23-20 loss resulted in plenty of discussion surrounding the NFL's new dynamic kickoff, which was first implemented in 2024. Former NFL quarterback Chase Daniel went off on the rule in an appearance on Kay Adams's Up & Adams Show.

NFL player prop picks and SGP bets for Seattle vs. Arizona on Thursday Night Football from the SportsLine Machine Learning Model AI