The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

A patient arriving in A&E or another clinical setting, with suspected or known infection and the risk of sepsis, requires immediate action. Antibiotic admission more than one hour after suspected ...

Sepsis is a critical global healthcare challenge, marked by complex and rapidly evolving symptoms, which can escalate with alarming speed leading to multi-organ failure. This leaves only a narrow ...

Twenty years after the groundbreaking meeting in Bellagio, Italy, that established the interdisciplinary enterprise of ...

The European Health Data Space Regulation has arrived but will its mandatory sharing requirement be its tour de force or Achilles’ heel? The Regulation amounts to an ambitious and laudable step ...

These plans have been a long time in the making. The intention to produce a strategy ‘to ensure the UK is able to offer a predictive, preventative and personalised health and care service for people ...

The UK is a recognised powerhouse for genomic science and medicine. Genomics England’s 100,000 Genomes Project is the largest sequencing project of its kind in the world and, building on these ...

The Wellcome Trust recently announced that they are funding a research programme to investigate synthetic human genomes, and Laura Blackburn, PHG Foundation’s Head of Science, had the opportunity to ...

On Friday the High Court ruled on the case of ABC v St George’s NHS Trust (and other NHS defendants). This is a significant decision with implications for a wide range of healthcare professionals ...

Polygenic scores aim to measure the cumulative effect of multiple genetic variants to make predictions about a person’s health. The most likely areas of potential use are in risk prediction, including ...

Dr. Khoury is the founding Director of the Office of Public Health Genomics at the U.S. Centers for Disease Control and Prevention. The Office was formed in 1998 and Dr Khoury served as the only ...

A recent consultation by the UK Medicines and Healthcare products Regulatory Agency (MHRA) indicates a welcome new direction for public and patient involvement (PPI). The MHRA proposed new five-year ...