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PharmaMastery on Instagram: "Drug of the day: Rosuvastatin 💊 One of the most powerful statins, targeting HMG-CoA reductase, the key enzyme in cholesterol synthesis. But here’s the exam pearl: the biggest LDL reduction happens because the liver increases LDL receptor expression, pulling more LDL out of circulation. So it works by blocking production AND increasing removal. Used in hypercholesterolemia and prevention of heart attacks and strokes. Brand name: Crestor. Major adverse effects: myalgi
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PharmaMastery on Instagram: "Drug of the day: Rosuvastatin 💊 One of the most powerful statins, targeting HMG-CoA reductase, the key enzyme in cholesterol synthesis. But here’s the exam pearl: the biggest LDL reduction happens because the liver increases LDL receptor expression, pulling more LDL out of circulation. So it works by blocking production AND increasing removal. Used in hypercholesterolemia and prevention of heart attacks and strokes. Brand name: Crestor. Major adverse effects: myalgi
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Rosuvastatin 💊 (High-Potency Statin) • Used for cholesterol control & heart protection • Strong LDL lowering effect • Long-lasting action (once daily) • Helps reduce cardiovascular risk ⭐ Unique Point: Rosuvastatin is a high-potency statin with longer effect and fewer CYP3A4 interactions compared to some other statins. ⚠️ Important Side Effects: • Muscle pain or weakness • Rare severe muscle injury • Mild reversible protein in urine (in some cases) • Antacids should not be taken together (keep
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