Adult-onset opsoclonus-myoclonus which is rare, striking and always demands a thorough workup. This chaotic eye movement and body jerking combination can be the tip of a neurologic iceberg. The differential diagnosis includes paraneoplastic syndromes and think about lung, breast, ovarian cancers and don't forget anti-Ri or anti-Hu antibodies. Always think about neuroblastoma. Also keep in mind autoimmune encephalitis (NMDA receptor, GAD65), post-infectious causes (especially West Nile or Epstein

Opsoclonus or ocular flutter #Opsoclonus and ocular #flutter are saccadic intrusions characterized by bursts of involuntary, back-to-back saccades without an intersaccadic interval. The oscillations are termed ocular flutter when they exist in the horizontal plane only and opsoclonus whey they are multidirectional in horizontal, vertical, and torsional planes. Ocular flutter is one of the manifestations of serotonin syndrome. The typical clinical manifestations include changes in : 1. mental sta